If your putting a new motor in, here is some info to consider:
1)Use pre-mix in the first tank or two in addition to the stock oil injection.
2)Warm up the engine before giving it more than 20% throttle. (you should always do this, not just during break in)
3)DON'T use synthetic oil until after the break-in is done.
4)Make sure your not running lean (Intake air leaks, clogged fuel filter, clogged carb, failing fuel pump, wrong jets, etc)
5)Make sure your oil injection system is working perfectly, with no cracked hoses or out of adjustment.
6)Put duct tape over the engine openings during the installation (intake, exhaust, spark plug hole, etc)
7)Before first firing the motor, ground the plug wires and fog the intake and the spark plug holes.
8)Heat cycle the motor 3 or 4 times before taking it for the first ride around the lake.
9)Keep it below 50% throttle for the first hour (ya right, never going to happen)
10)Keep it below 75% throttle for the first tank of gas. (ya right, never going to happen)
ASSUME that it is going to break down, and have a backup plan of some sort. Stay close to shore, bring a buddy boat, etc.